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THE INCREASE OF THE REDUCED FORM GLUTATHIONE IN THE LIVER TISSUE AS A POSSIBLE FACTOR ETHANOL TOXICITY
Zhukova Olga Yuryevna1, Didenko Kristina Nikolaevna2
1Federal State Funded Educational Institution for Higher Education Omsk State Medical University Ministry of Public Health Russian Federation, senior lecturer, PhD in Medical sciences
2Federal State Funded Educational Institution for Higher Education Omsk State Medical University Ministry of Public Health Russian Federation, laboratory assistant
1Federal State Funded Educational Institution for Higher Education Omsk State Medical University Ministry of Public Health Russian Federation, senior lecturer, PhD in Medical sciences
2Federal State Funded Educational Institution for Higher Education Omsk State Medical University Ministry of Public Health Russian Federation, laboratory assistant
Abstract
In this article, information about the intracellular level of re-duced glutathione, the parameters of iron-induced chemiluminescence activity of antioxidant enzymes in the liver tissue of rats in conditions of experimental modeling of acute alcohol intoxication. Discussed the impact of introduction of ethyl alcohol in the indicators reflecting the pro- and antioxidant status of cells.
Keywords: alcohol, alcohol intoxication, alcoholism, antioxidants, chemiluminescence, ethanol, free radicals, glutathione, liver hepatocytes, reactive oxygen species, sulfhydryl groups
Category: 03.00.00 Biology
Article reference:
The increase of the reduced form glutathione in the liver tissue as a possible factor ethanol toxicity // Modern scientific researches and innovations. 2016. № 10 [Electronic journal]. URL: https://web.snauka.ru/en/issues/2016/10/72891
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