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THE ELECTROPHYSIOLOGICAL MODEL OF THYROXINE, LYDASE AND IODMETHYLATE 2 (DIMETHYLAMINO) ETHYL ESTER N –(P-METOXYBENZOIL) – D, L – FENILALANYN INFLUENCE UNDER ORGANIC LESIONS OF SPINAL CORD
Khachatryan T.S.1, Karapetyan I.R.2, Topuzyan V.O.3, Avagyan A.E.4
1Institute of Applied Problems of Physics of National Academy of Sciences of Republic of Armenia
2Institute of Physiology named after L.A. Orbeli of National Academy of Sciences of Republic of Armenia
3A.L. Mndzhoyan Institute of fine organic chemistry of National Academy of Sciences of Republic of Armenia
4"TIAR" LTD
1Institute of Applied Problems of Physics of National Academy of Sciences of Republic of Armenia
2Institute of Physiology named after L.A. Orbeli of National Academy of Sciences of Republic of Armenia
3A.L. Mndzhoyan Institute of fine organic chemistry of National Academy of Sciences of Republic of Armenia
4"TIAR" LTD
Abstract
The results of our experimental studies have shown that the complex influence of thyroxine, lydase and and iodmethylate 2 (dimethylamino) ethyl ester N –(p-metoxybenzoil – D, L - fenilalanyn) on the electrical excitability of single pyramidal neurons of sensomotor zones of cortex was provided on rats with left – side lateral hemisection on T8 – T9 level. The investigations have shown a recovery of supporting, locomotor and sensory functions in rats have been administrated the enzyme lydase and thyroid hormone – thyroxine and choline ester – and iodmethylate 2 (dimethylamino) ethyl ester N –(p-metoxybenzoil – D, L - fenilalanyn). The least intensive inflamatory and destructive processes and a slightly noticeable, loose scar in the lesioned half of the spinal cord are observed in animals treated with lydase, thyroxine and and iodmethylate 2 (dimethylamino) ethyl ester N –(p-metoxybenzoil – D, L - fenilalanyn).
Keywords: L – фенилаланина
Category: 03.00.00 Biology
Article reference:
The electrophysiological model of thyroxine, lydase and iodmethylate 2 (dimethylamino) ethyl ester N –(p-metoxybenzoil) – D, L - fenilalanyn influence under organic lesions of spinal cord // Modern scientific researches and innovations. 2012. № 8 [Electronic journal]. URL: https://web.snauka.ru/en/issues/2012/08/16431
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