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PARTICULARITIES OF THE ACTION OF THE OVER LOW DOSAGES OF SOME CHOLINE ESTERS AND AMIDES ON EXTRACELLULAR ELECTRICAL ACTIVITY OF RAT’S SPINAL CORD SINGLE MOTONEURONS IN CONDITIONS OF EXPERIMENTAL HYPERTHYROIDISM
Khachatryan T.S.1, Avagyan A.E.2, Topuzyan V.O.3
1Institute of Applied Problems of Physics of National Academy of Sciences of Republic of Armenia
2"TIAR" LTD
3A.L. Mndzhoyan Institute of fine organic chemistry of National Academy of Sciences of Republic of Armenia
1Institute of Applied Problems of Physics of National Academy of Sciences of Republic of Armenia
2"TIAR" LTD
3A.L. Mndzhoyan Institute of fine organic chemistry of National Academy of Sciences of Republic of Armenia
Abstract
In these series of investigations the issue of the use of 3 choline synthetic derivates – iod – methylate 2 – (dimethylamino) ethyl – N – (p – metoxybenzoil) – DL – fenilalanyn ether, iod – methylate 2 – (dimethylamino) ethyl – N – benzoil – DL – valin ether and iod – methylate 2 – (dimethylamino) ethyl – N – (p – metoxybenzoil) – DL – fenilalanyn amid on rats with experimental hyperthyroidism is discussed. The obtained results show the positive effect of over small dozes of these substances complex on extracellular background and evoked electric activity of rat’s spinal cord single motoneurons in condition of hyperthyroidism. The recording and analysis of the electrophysiological factors of rats spinal cord was done by means of special software in on-line mode.
Category: 03.00.00 Biology
Article reference:
Particularities of the action of the over low dosages of some choline esters and amides on extracellular electrical activity of rat's spinal cord single motoneurons in conditions of experimental hyperthyroidism // Modern scientific researches and innovations. 2012. № 8 [Electronic journal]. URL: https://web.snauka.ru/en/issues/2012/08/16439
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